I was running Gentoo on my Dell Inspiron 7000 laptop but today I've gone and slicked it. I'm going to switch my laptop over to use Debian. Gentoo is pretty neat, but it takes me days to compile GNOME and I'm hitting the point where the novelty is wearing off and I want to actually use my laptop.
Anyhow, I recommend it for folks with more powerful machines. I enjoyed running it and learned a lot in the process.